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The Complete Guide to Hyperbaric Oxygen Therapy: Everything You Need to Know in 2025

Updated: Jun 4

At Elixir Health and Wellness in Bethlehem, PA, we believe in the power of evidence-based healing. This comprehensive guide answers the most common questions about hyperbaric oxygen therapy (HBOT) with scientific backing.


Your Complete Guide to Hyperbaric Oxygen Therapy (HBOT)


This Complete Guide will cover the most frequently asked questions I have received over the last couple of years in business. It will give you an in-depth starting point for everything you might want to know about Hyperbaric Oxygen Therapy (HBOT).


Please note that at Elixir Health and Wellness we only have mild Hyperbaric Oxygen (mHBOT) chambers. This article is a deep dive into everything-HBOT to help you on your journey figuring out what's best for you.


mild hyperbaric oxygen therapy chambers and red light therapy at Elixir Health and Wellness
Elixir Health and Wellness in Bethlehem, PA offers a warm and welcoming environment to support your wellness journey; featured: mild Hyperbaric Oxygen Therapy, Red Light Therapy, Compression Therapy.

For the majority of my adult life, I've been traveling the world collecting anecdotal evidence, reading research papers, and meeting with doctors and shamans. My goal has been to find what I believe is the "elixir" of life. What lever can I pull with the least effort to increase my vitality, lifespan, and quality of life? Oxygen, especially under pressure, stands out as one of those levers. When I returned to the United States, I wanted to share this technology with my community. Thus, I opened Elixir Health and Wellness in Bethlehem, Pennsylvania—just steps away from the Northside Historic District, now recognized as a World Heritage Site.


Continue reading to answer your most commonly asked questions! You can read the whole guide or jump directly to the topic that interests you.


1: What is Hyperbaric Oxygen Therapy and How Does It Work?


HBOT stands for Hyperbaric Oxygen Therapy. These treatments involve chamber pressures of 1.5 ATA and up. On the other hand, mHBOT refers to mild Hyperbaric Oxygen Therapy, with chamber pressures of 1.3 ATA to 1.5 ATA.


For clarity, I'll use HBOT to encompass both types unless specified otherwise.


Both HBOT and mHBOT involve breathing elevated levels of oxygen within a pressurized chamber. Think of it as giving your body's healing mechanisms a supercharged boost.


The Science Behind Hyperbaric Healing


Under normal conditions, oxygen travels throughout your body via red blood cells. However, in a hyperbaric chamber, the increased pressure allows oxygen to dissolve directly into your plasma, cerebrospinal fluid, and lymphatic system. This results in oxygen concentrations 15-20 times higher than normal atmospheric levels!


Key Mechanisms of HBOT


The therapy operates through several essential mechanisms:


  • Enhanced Oxygen Delivery: Increased atmospheric pressure (typically 1.3-3.5 times normal) forces more oxygen into your bloodstream and tissues, reaching areas with reduced blood flow.


  • Angiogenesis Stimulation: HBOT promotes the creation of new blood vessels, improving long-term circulation to damaged tissues. Studies indicate this process can boost capillary density by up to 40%.


  • Reduced Inflammation: The therapy modulates inflammatory responses, helping to manage harmful inflammation while preserving beneficial healing processes.


  • Antimicrobial Effects: High oxygen levels create an environment hostile to anaerobic bacteria and enhance white blood cell functionality.


2: What Does Hyperbaric Oxygen Therapy Do? Conditions and Applications


In the United States, HBOT has FDA approval for 14 specific conditions, including:


  • Air or Gas Embolism: Presence of air or gas bubbles in blood vessels.

  • Carbon Monoxide Poisoning: Poisoning by carbon monoxide.

  • Decompression Sickness: A diving-related condition caused by rapid ascent.

  • Crush Injury and Compartment Syndrome: Injuries from crushing or compression of body parts, impacting blood flow.

  • Gas Gangrene: Severe muscle infections caused by bacteria.

  • Severe Anemia: Conditions involving insufficient red blood cells.

  • Thermal Burns: Burns caused by heat.

  • Radiation Tissue Injury: Damage to tissues induced by radiation.

  • Skin Grafts at Risk of Tissue Death: Skin grafts facing complications with healing.

  • Refractory Osteomyelitis: Chronic bone infections.

  • Non-healing Wounds: Difficult-to-heal wounds like diabetic foot ulcers.

  • Severe Skin and Bone Infections: Significant infections of skin and bone.

  • Painless Sudden Vision Loss: Vision loss in one eye due to blocked blood flow.

  • Sudden Hearing Loss: Complete hearing loss without an identified cause.


All FDA-approved conditions specifically apply to HBOT (2.0 ATA+), with the exception of decompression sickness, which can use mHBOT (1.3 ATA+).


Emerging Applications: What Research Shows


While traditional uses of HBOT are well-established, emerging evidence suggests benefits in conditions like long-COVID, traumatic brain injury, PTSD, and chronic fatigue syndrome. In the U.S., those are classified as off-label conditions. Most off-label conditions potentially treatable with either mHBOT or HBOT.


In Europe, particularly in Russia, over 40 approved conditions are treated with HBOT. In countries like Japan and China, that number exceeds 60. Some of these conditions include:


  • Brain Injury Recovery: Studies suggest HBOT may help traumatic brain injury (TBI) recovery by reducing swelling and promoting neuroplasticity. Conditions like brain fog, concussions, and Alzheimer’s are also noted. A 2020 systematic review indicated modest cognitive function improvements, but further research is needed.


  • Stroke Recovery: Research implies HBOT may enhance recovery outcomes if used within critical time frames post-stroke, potentially extending the therapeutic window for intervention. Optimal results tend to occur within six months post-rehabilitation clearance.


  • Wound Healing: The therapy greatly accelerates healing in wounds by enhancing collagen synthesis and fighting infection. This is particularly beneficial for cosmetic procedures, with success rates for diabetic ulcers reported between 70-85% in clinical studies.



The Recline mHBOT Chamber at Elixir Health and Wellness
The Recline mHBOT Chamber at Elixir Health and Wellness

3: Does Hyperbaric Oxygen Therapy Work? The Evidence


The short answer is: Yes.


For approved conditions (HBOT), effectiveness varies:


  • Diabetic foot ulcers: 70-85% healing rate

  • Radiation cystitis: 80-90% improvement rate

  • Carbon monoxide poisoning: Significantly reduces neurological sequelae

  • Sudden hearing loss: 50-60% improvement when used within 90 days


For off-label uses, evidence is limited but expanding. Always consult healthcare providers regarding realistic expectations for your condition. We offer free 15-minute phone consultations if you wish to discuss your situation.


4: Safety Profile: Is Hyperbaric Oxygen Therapy Safe?


HBOT is generally safe when administered correctly. However, like any medical treatment, it carries some risks.


Common Side Effects (Mild and Temporary)


  • Ear discomfort or pressure

  • Temporary vision changes

  • Fatigue

  • Claustrophobia

  • Sinus congestion


Rare but Serious Complications


  • Pneumothorax (collapsed lung): Occurs in less than 1% of cases.

  • Oxygen toxicity: Extremely rare with proper protocols.

  • Barotrauma: Ears or sinuses may experience pressure-related issues.


Most Common Complication: Barotrauma to the middle ear occurs in about 2% of patients. Typically, this is mild and resolves quickly.


5: Treatment Protocols: How Long, How Often, How Many Sessions?


Protocols vary significantly based on individual needs. An athlete seeking an energy boost may require a single session, while someone aiming to improve brain fog might need 20 sessions. Some clients notice improvements with sessions twice a month, while others may need them twice daily.


If you'd like to discuss your specific needs before booking a session at Elixir Health and Wellness, we offer a free 15-minute consultation. Please note, we are a wellness center and do not provide general medical consultations.


Typical Treatment Schedule


  • Session Length: 60-120 minutes

  • Frequency: 1-5 days per week (Monday-Friday)

  • Total Sessions: Varies by condition (examples below)

- Energy boost: 1-5 sessions

- Cosmetic procedure: 5-10 sessions

- Athlete off-season: 10-20 sessions

- Long-COVID: 20-40 sessions

- Lyme inflammation: 20-40 sessions

- Brain injury: 40-80 sessions

- Anti-aging: 20-80 sessions


What to Expect During Treatment


Our mHBOT chambers resemble a spacious bubble, a tent, or a first-class airplane seat. During compression and decompression, you’ll feel ear pressure similar to that experienced when flying. Most clients read, catch up with friends, do emails, watch movies, listen to music, or sleep during their sessions.


6: Cost and Insurance Coverage: The Financial Reality


Typical Costs


  • Per session: $80-$500

  • Complete treatment course: $80-$20,000

  • Facility type affects pricing: Hospital-based options usually cost more than standalone clinics. HBOT is generally pricier than mHBOT.


Insurance Coverage


Medicare: Covers HBOT for FDA-approved conditions when medical necessity is established, provided in approved facilities.


Private Insurance: Coverage varies significantly. Pre-authorization is usually required.


What’s Typically Covered:

  • Diabetic foot wounds

  • Radiation tissue damage

  • Decompression sickness

  • Carbon monoxide poisoning


What’s Rarely Covered:

  • Brain injury rehabilitation

  • Lyme disease

  • Anti-aging applications

  • Most off-label uses


All services at Elixir Health and Wellness are HSA/FSA eligible, but we do not accept other forms of insurance. We don’t offer HBOT protocols for FDA-approved conditions that could be covered by insurance. If you have this benefit, it's worth asking your clinic about it.


The Seated mHBOT Chamber at Elixir Health and Wellness
The Seated mHBOT Chamber at Elixir Health and Wellness

7: Who Can Administer HBOT?


HBOT must be given under medical supervision. This includes:


  • Physician oversight: A doctor trained in hyperbaric medicine.

  • Certified technicians: Operators certified in chamber safety and protocols.

  • Proper facility: An accredited hyperbaric facility with emergency protocols.


mHBOT is a lower-risk treatment, so provider training may not always be guaranteed. It’s crucial to inquire about the provider's experience with HBOT and how they developed their protocols. If you don’t trust your provider, be cautious following their advice.


At Elixir Health and Wellness, we developed our initial protocols alongside a leading Hyperbaric Medicine specialist. We have been refining them under a clinical setting, based on real results from actual clients. We stay current with the latest research and attend conferences to maintain our edge, ensuring you receive high-quality care. We also refer out for certain medical conditions that fall outside our expertise. Your safety and comfort remain our top priority.


8: At-Home Hyperbaric Chambers: Mild HBOT Options


Mild Hyperbaric Chambers, often referred to as Soft Chambers, are the primary home-use options available:


  • Pressure: 1.3-1.5 ATA (compared to clinical settings of 2.0-3.0 ATA)

  • Oxygen: Either atmospheric or concentrated oxygen via mask (not pure oxygen environments).

  • Cost: $3,000-$30,000 for purchase; $500-$3,500/month for rental.


When purchasing a chamber, ensure the company is reputable. You don't want a unit that fails on your first use without a return option.


Rental Requirements


  • Physician prescription typically required.

  • Training on safe operation is mandatory.

  • Some companies require liability waivers.

  • Regular maintenance and safety checks might also be necessary.


Effectiveness Comparison


Mild HBOT offers benefits but is less potent than clinical HBOT. Research indicates favorable effects for certain conditions, but outcomes may be less dramatic than seen in clinical treatments. Some clients with medical needs might qualify for a home unit capable of reaching 2.0 ATA, but these units are much more expensive and require supervision.


If you're interested in purchasing an at-home unit, we can connect you with a trusted company. Just use the Contact Us form.


9: Should You Try Hyperbaric Oxygen Therapy?


You might consider HBOT if you have:

  • An FDA-approved condition

  • Chronic wounds not responding to standard treatment

  • Radiation tissue damage

  • Specific neurological conditions that show evidence supporting use


You could consider mHBOT if you are:

  • Interested in biohacking, longevity, and anti-aging

  • An athlete, whether weekend, professional, or hobbyist

  • Experiencing brain fog stemming from any condition

  • Seeking alternative or holistic treatments


Red Flags (Avoid HBOT if you have):


  • Untreated pneumothorax

  • Certain lung issues

  • Uncontrolled high fever

  • Medications that interact with high oxygen levels


It's essential to conduct thorough research, ask as many questions as you need, and book with facilities you trust.


mHBOT at Elixir Health and Wellness


Hyperbaric oxygen therapy represents a valuable tool within modern medicine’s healing repertoire. Although not a miracle cure, it offers genuine benefits for various conditions supported by solid scientific evidence.


At Elixir Health and Wellness in Bethlehem, PA, we provide evidence-based HBOT treatments in a comfortable and professional environment. We ensure safe and effective treatment protocols tailored specifically to your needs.


Was this Complete Guide to Hyperbaric Oxygen Therapy helpful? Have you used HBOT before? Leave a comment below with your thoughts!


Ready to explore if mHBOT is right for you? Contact our team for a free consultation. We'll review your medical history, discuss realistic expectations, and create a personalized treatment plan based on the latest scientific evidence.



IMPORTANT MEDICAL DISCLAIMER The information provided in this article is for educational and informational purposes only and is not intended as medical advice. This content should not be used as a substitute for professional medical advice, diagnosis, or treatment. ALWAYS CONSULT YOUR HEALTHCARE PROVIDER before starting any new treatment, including hyperbaric oxygen therapy, compression therapy, or red light therapy. Only qualified healthcare professionals can determine if these treatments are appropriate for your specific medical condition. INDIVIDUAL RESULTS MAY VARY. The outcomes described in research studies and testimonials may not be typical and cannot be guaranteed for any individual. TREATMENT DECISIONS should be made in consultation with your healthcare provider based on your individual medical history, current health status, and specific needs. INSURANCE COVERAGE information provided is general in nature and may not reflect your specific policy benefits. Always verify coverage directly with your insurance provider. NO DOCTOR-PATIENT RELATIONSHIP is created by reading this content. This information does not replace the need for proper medical evaluation and care. The content has not been evaluated by the Food and Drug Administration (FDA) and is not intended to diagnose, treat, cure, or prevent any disease. Elixir Health and Wellness encourages you to make healthcare decisions based on your research and in partnership with qualified healthcare professionals.


Last updated: May 23, 2025

 
 
 

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